Iselin's Disease – 5th Metatarsal Pain in Young Athletes
Iselin's disease causes pain on the outside of the foot in young athletes. Learn about symptoms, diagnosis, and how conservative treatment returns you to sport.
By Dr. Sean Griffin
Iselin's Disease – 5th Metatarsal Pain in Young Athletes Are you a young athlete experiencing pain on the outside of your foot? Iselin's disease might be the reason you're sidelined from your sport. This condition, which affects the fifth metatarsal bone, is increasingly common in active adolescents. At Central Florida Foot & Ankle Institute, we understand the challenges young athletes face when foot pain interrupts training and competition. Let's explore what Iselin's disease is and how we can get you back in the game. What Is Iselin's Disease? Iselin's disease is an overuse injury affecting the apophysis (growth plate) of the fifth metatarsal bone—the long bone on the outside of your foot. Also called fifth metatarsal apophysitis, this condition occurs almost exclusively in young athletes aged 10 15, particularly during periods of rapid growth. The condition causes pain and inflammation where the peroneus brevis muscle tendon attaches to the fifth metatarsal, creating a painful bump on the outside of the foot. Unlike Freiberg's infraction, Iselin's disease doesn't involve bone death. Instead, it's an inflammation of the growth plate caused by repeated stress and pulling from the attached muscle and tendon. Understanding the Causes The Growth Plate Connection During adolescence, growth plates are the last areas of your bones to harden and mature. This makes them particularly vulnerable to stress and injury. The fifth metatarsal apophysis is especially susceptible because of the significant forces it experiences during running, jumping, and lateral (side to side) movements. Repetitive Stress and Overuse Iselin's disease develops from repetitive stress to the fifth metatarsal. Sports that place heavy demands on this area are common culprits: Soccer – with its frequent direction changes and lateral movements Basketball – demanding quick cuts and pivoting Gymnastics – requiring powerful toe off movements Track and field – especially sprinting and jumping events Volleyball – with its explosive lateral movements Training Errors Many young athletes develop Iselin's disease when they: Suddenly increase training intensity or volume Don't take adequate rest between training sessions Don't properly warm up before competition Use improper technique during sport specific movements Haven't developed sufficient conditioning Biomechanical Factors Certain foot structures increase vulnerability. If you have: High arched feet (cavus foot) Ankle instability Tight calf muscles Inversion ankle sprains in your history You may be at higher risk for developing Iselin's disease. Recognizing the Symptoms Where the Pain Occurs The classic presentation of Iselin's disease is pain and tenderness on the outside of the foot, specifically where the peroneus brevis tendon attaches to the fifth metatarsal base. Athletes often describe this as a painful bump on the outside of the foot. Activity Related Pain You might notice: Pain that starts or worsens during sports Immediate relief when you stop the activity Soreness the day after competition or practice Difficulty with lateral cutting or pivoting movements Reluctance to push off on the outer foot Swelling on the outside of the midfoot Impact on Performance As the condition progresses, even walking can become uncomfortable. Many athletes report limping, difficulty with running, and inability to participate in their sport at full intensity. How We Diagnose Iselin's Disease Physical Examination When you visit Central Florida Foot & Ankle Institute, our sports podiatrists will assess your foot carefully. We'll look for a prominent bony prominence on the outside of your foot and palpate the area to identify specific tenderness. We'll also evaluate your ankle stability, muscle flexibility, and walking pattern. Imaging Studies X rays reveal characteristic findings: Prominence of the fifth metatarsal tuberosity Possible fragmentation or irregularity of the apophysis Swelling in the soft tissues around the bone X rays help us confirm the diagnosis and rule out other conditions like Jones fractures or peroneal tendon problems. Ultrasound allows us to visualize the peroneus brevis tendon and assess inflammation, helping us understand the full extent of the injury. Treatment Options for Young Athletes Conservative Care Is the First Step Most cases of Iselin's disease respond well to conservative treatment, allowing young athletes to return to sport without surgery. Rest and Activity Modification The foundation of treatment is removing the repetitive stress that caused the problem: Temporarily avoid the sport or activity that triggered pain Switch to low impact cross training (swimming, cycling, strength training) Gradually return to your sport as pain resolves Use "relative rest"—staying active without aggravating the injury Ice and Anti Inflammatory Measures Regular icing after activities reduces inflammation and pain. Many athletes benefit from applying ice for 15 20 minutes several times daily, esp